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Difference between revisions of "User:Gabriela Persinoti"
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| + | Gabriela Persinoti is the head of Integrative Omics team of the Brazilian Biorenewables National Laboratory [https://lnbr.cnpem.br/en/ LNBR], from the Brazilian National Center for Research in Energy and Materials [https://cnpem.br/en/ CNPEM]. She obtained her B.Sc. in Biomedical Informatics from the University of São Paulo (2006) and completed her PhD in Genetics (2012) at the Medical School of Ribeirão Preto (University of São Paulo). Her research interests are focused on the investigation of microbiomes from diverse environments for the discovery of novel enzymes. | ||
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| + | She has contributed to the investigation of CAZymes from families [[GH26]] <cite>Mandelli2020</cite>, [[GH39]] <cite>Morais2020</cite>, [[GH128]] <cite>Santos2020</cite>, the xyloglucan depolymerization locus from ''Xanthomonas citri'' <cite>Vieira2021</cite>, and the N-glycan depolymerization loci from ''Bifidobacterium longum'' <cite>Cordeiro2023</cite>. | ||
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| + | Particularly notable work includes the investigation of the gut microbiome of the largest living rodent, the capybara <cite>Cabral2022</cite>, that led to the discovery of [[Carbohydrate Binding Module Family 89|CBM89]], and [[GH173]] novel CAZy families and [[GH5]]_57 subfamily <cite>Martins2022</cite>. | ||
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#Santos2020 pmid=32451508 | #Santos2020 pmid=32451508 | ||
| − | + | #Vieira2021 pmid=34193873 | |
#Cabral2022 pmid=35110564 | #Cabral2022 pmid=35110564 | ||
| + | #Martins2022 pmid=36322419 | ||
#Cordeiro2023 pmid=36443572 | #Cordeiro2023 pmid=36443572 | ||
Latest revision as of 10:48, 11 July 2023
Gabriela Persinoti is the head of Integrative Omics team of the Brazilian Biorenewables National Laboratory LNBR, from the Brazilian National Center for Research in Energy and Materials CNPEM. She obtained her B.Sc. in Biomedical Informatics from the University of São Paulo (2006) and completed her PhD in Genetics (2012) at the Medical School of Ribeirão Preto (University of São Paulo). Her research interests are focused on the investigation of microbiomes from diverse environments for the discovery of novel enzymes.
She has contributed to the investigation of CAZymes from families GH26 [1], GH39 [2], GH128 [3], the xyloglucan depolymerization locus from Xanthomonas citri [4], and the N-glycan depolymerization loci from Bifidobacterium longum [5].
Particularly notable work includes the investigation of the gut microbiome of the largest living rodent, the capybara [6], that led to the discovery of CBM89, and GH173 novel CAZy families and GH5_57 subfamily [7].
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- Mandelli F, de Morais MAB, de Lima EA, Oliveira L, Persinoti GF, and Murakami MT. (2020). Spatially remote motifs cooperatively affect substrate preference of a ruminal GH26-type endo-β-1,4-mannanase. J Biol Chem. 2020;295(15):5012-5021. DOI:10.1074/jbc.RA120.012583 |
- de Morais MAB, Polo CC, Domingues MN, Persinoti GF, Pirolla RAS, de Souza FHM, Correa JBL, Dos Santos CR, and Murakami MT. (2020). Exploring the Molecular Basis for Substrate Affinity and Structural Stability in Bacterial GH39 β-Xylosidases. Front Bioeng Biotechnol. 2020;8:419. DOI:10.3389/fbioe.2020.00419 |
- Santos CR, Costa PACR, Vieira PS, Gonzalez SET, Correa TLR, Lima EA, Mandelli F, Pirolla RAS, Domingues MN, Cabral L, Martins MP, Cordeiro RL, Junior AT, Souza BP, Prates ÉT, Gozzo FC, Persinoti GF, Skaf MS, and Murakami MT. (2020). Structural insights into β-1,3-glucan cleavage by a glycoside hydrolase family. Nat Chem Biol. 2020;16(8):920-929. DOI:10.1038/s41589-020-0554-5 |
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