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Difference between revisions of "Glycoside Hydrolase Family 61"
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=== GH61 is a deleted family === | === GH61 is a deleted family === | ||
| − | The enzymes in this family were originally classified as a glycoside hydrolases (GH61) based on very weak endo-1,4-beta-D-glucanase activity in one family member. They are now reclassified into [[ | + | The enzymes in this family were originally classified as a glycoside hydrolases (GH61) based on very weak endo-1,4-beta-D-glucanase activity in one family member. They are now reclassified into [[Auxiliary Activity Family 9]] in CAZy <cite>Levasseur2013</cite>. AA9 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); cleavage of cellulose chains with oxidation of various carbons (C-1, C-4 and C-6) has been reported several times in the literature (see <cite>Hemsworth2013</cite> and references therein). |
'''References''' | '''References''' | ||
Revision as of 18:52, 26 August 2013
- Responsible Curator: ^^^Bernard Henrissat^^^
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This family has been deleted from the CAZy classification. A specific explanation may be found below.
GH61 is a deleted family
The enzymes in this family were originally classified as a glycoside hydrolases (GH61) based on very weak endo-1,4-beta-D-glucanase activity in one family member. They are now reclassified into Auxiliary Activity Family 9 in CAZy [1]. AA9 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); cleavage of cellulose chains with oxidation of various carbons (C-1, C-4 and C-6) has been reported several times in the literature (see [2] and references therein).
References
- Levasseur A, Drula E, Lombard V, Coutinho PM, and Henrissat B. (2013). Expansion of the enzymatic repertoire of the CAZy database to integrate auxiliary redox enzymes. Biotechnol Biofuels. 2013;6(1):41. DOI:10.1186/1754-6834-6-41 |
- Hemsworth GR, Davies GJ, and Walton PH. (2013). Recent insights into copper-containing lytic polysaccharide mono-oxygenases. Curr Opin Struct Biol. 2013;23(5):660-8. DOI:10.1016/j.sbi.2013.05.006 |
| CAZy DB links | |
| https://www.cazy.org/AA9.html | |
| https://www.cazy.org/GH61.html |