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Difference between revisions of "User:Leila LoLeggio"
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== Short biographical sketch == | == Short biographical sketch == | ||
| − | Italian, born in Palermo 1971. Educated in Biochemistry at the University of Bath, during which had two inspiring introductions to the world of research in the groups of Roy Jones at the Babraham station and Angelika Noegel at the Max-Planck Institute for Biochemistry in Munich. Obtained a PhD in Crystallography from Birkbeck College, London, in 1997. In fact my PhD research was carried out at the Institute of Food Research in Reading, under the supervision of | + | Italian, born in Palermo 1971. Educated in Biochemistry at the University of Bath, during which had two inspiring introductions to the world of research in the groups of Roy Jones at the Babraham station and Angelika Noegel at the Max-Planck Institute for Biochemistry in Munich. Obtained a PhD in Crystallography from Birkbeck College, London, in 1997. In fact my PhD research was carried out at the Institute of Food Research in Reading, under the supervision of [[User:Richard Pickersgill|Richard Pickersgill]]. The project revolved around structure determination of xylanases and cellulases, and I was fortunate by being involved in the establishment of the 4/7 superfamily <cite>Jenkins1995</cite>, then to become Clan GH-A <cite>Henrissat1995</cite>. |
| − | I was then post-doctoral fellow in the group of | + | I was then post-doctoral fellow in the group of [[User:Sine Larsen|Sine Larsen]], at the Department of Chemistry, University of Copenhagen, first funded by a personal EMBO fellowship and later by other grants, until 2003, when I obtained a permanent position as Associate Professor in the same Department. In 2005 I became Research Group leader of the Biophysical Chemistry Group, still in the same Department. In 2013 the Biophysical Chemistry Group became part of the Bioinorganic and Biophysical Chemistry Section. Studies on the structure and function of carbohydrate active enzymes remains one of my major areas of research here in Copenhagen. My other main branch of research is on transcription factors. |
| − | I have either determined or contributed to structure determination, and structure/function and mechanistic elucidation in of a number of CAZY in [[GH5]], [[GH9]], [[GH10]], [[GH13]], [[GH26]], [[GH31]], [[GH36]], [[GH53]] and [[ | + | I have either determined or contributed to structure determination, and structure/function and mechanistic elucidation in of a number of CAZY in [[GH5]], [[GH9]], [[GH10]], [[GH13]], [[GH26]], [[GH31]], [[GH36]], [[GH53]], [[PL4]] and [[AA9]]. Some of my articles on CAZYs are in the reference list below <cite>Harris1994 LeNours2004 Ernst2006 Ryttersgaard2002 LeNours2003 Ryttersgaard2004 LeNours2009</cite>. |
References | References | ||
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#Henrissat1995 pmid=8643635 | #Henrissat1995 pmid=8643635 | ||
#Harris1994 pmid=7881909 | #Harris1994 pmid=7881909 | ||
| + | #LeNours2004 pmid=16171384 | ||
| + | #Ernst2006 pmid=16580018 | ||
| + | #Ryttersgaard2002 pmid=12484750 | ||
| + | #LeNours2003 pmid=12761390 | ||
| + | #Ryttersgaard2004 pmid=15312766 | ||
| + | #LeNours2009 pmid=19089956 | ||
| + | |||
</biblio> | </biblio> | ||
[[Category:Contributors|LoLeggio, Leila]] | [[Category:Contributors|LoLeggio, Leila]] | ||
Latest revision as of 13:34, 18 December 2021
Associate Professor and Research Group leader at the Department of Chemistry, University of Copenhagen.
Short biographical sketch
Italian, born in Palermo 1971. Educated in Biochemistry at the University of Bath, during which had two inspiring introductions to the world of research in the groups of Roy Jones at the Babraham station and Angelika Noegel at the Max-Planck Institute for Biochemistry in Munich. Obtained a PhD in Crystallography from Birkbeck College, London, in 1997. In fact my PhD research was carried out at the Institute of Food Research in Reading, under the supervision of Richard Pickersgill. The project revolved around structure determination of xylanases and cellulases, and I was fortunate by being involved in the establishment of the 4/7 superfamily [1], then to become Clan GH-A [2].
I was then post-doctoral fellow in the group of Sine Larsen, at the Department of Chemistry, University of Copenhagen, first funded by a personal EMBO fellowship and later by other grants, until 2003, when I obtained a permanent position as Associate Professor in the same Department. In 2005 I became Research Group leader of the Biophysical Chemistry Group, still in the same Department. In 2013 the Biophysical Chemistry Group became part of the Bioinorganic and Biophysical Chemistry Section. Studies on the structure and function of carbohydrate active enzymes remains one of my major areas of research here in Copenhagen. My other main branch of research is on transcription factors.
I have either determined or contributed to structure determination, and structure/function and mechanistic elucidation in of a number of CAZY in GH5, GH9, GH10, GH13, GH26, GH31, GH36, GH53, PL4 and AA9. Some of my articles on CAZYs are in the reference list below [3, 4, 5, 6, 7, 8, 9].
References
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- Le Nours J, De Maria L, Welner D, Jørgensen CT, Christensen LL, Borchert TV, Larsen S, and Lo Leggio L. (2009). Investigating the binding of beta-1,4-galactan to Bacillus licheniformis beta-1,4-galactanase by crystallography and computational modeling. Proteins. 2009;75(4):977-89. DOI:10.1002/prot.22310 |