User:Shinya Fushinobu

I am a Professor at Laboratory of Enzymology in Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo located in Tokyo, Japan. Raised in Kure, Hiroshima, Japan. I obtained Ph.D degree in Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo in 1999. My research interests concern structure and function of enzymes, mainly those of Carbohydrate-Active enZymes. My home page is here. I contributed to three-dimensional structure determination of

• GH1 Phanerochaete chrysosporium β-glucosidase 1B (BGL1B) [1]
• GH1 Metagenomic β-Glucosidase (Td2F2) [2]
• GH3 Kluyveromyces marxianus β-glucosidase (KmBglI) [3]
• GH3 Aspergillus aculeatus β-glucosidase (AaBGL1) [4]
• GH8 Bacillus halodurans reducing-end xylose-releasing exo-oligoxylanase (Rex) [5]
• GH9 Photobacterium profundum exo-β-D-glucosaminidase (PpGlcNase) [6]

• GH10 Clostridium stercorarium xylanase B (XynB) [7]
• GH11 Aspergillus kawachii xylanase C (XynC) [8]
• GH20 Bifidobacterium bifidum lacto-N-biosidase (BbLNBase) [9]
• GH26 β-mannanase from a symbiotic protist of the termite Reticulitermes speratus (RsMan26C) [10]
• GH29 Bifidobacterium longum subsp. infantis 1,3-1,4-α-L-fucosidase (BiAfcB) [11]
• GH42 Thermus thermophilus β-galactosidase (A4-β-Gal) Family First [12]
• GH45 Phanerochaete chrysosporium endoglucanase (PcCel45A) [13]

• GH51 Thermotoga maritima α-L-arabinofuranosidase (Tm-AFase) [14]
• GH54 Aspergillus kawachii α-L-arabinofuranosidase B (AkAbfB) Family First plus identification of CBM42 [15]
• GH55 Phanerochaete chrysosporium β-1,3-glucanase (Lam55A) Family First [16]
• GH57 Thermococcus litoralis 4-α-glucanotransferase (TLGT) Family First [17]
• GH65 Caldicellulosiruptor saccharolyticus kojibiose phosphorylase (CsKP) [18]
• GH65 Bacillus selenitireducens 2-O-α-glucosylglycerol phosphorylase (GGP) [19]
• GH94 Vibrio proteolyticus chitobiose phosphorylase (ChBP) Family First [20]
• GH94 Cellvibrio gilvus cellobiose phosphorylase (CBP) [21]
• GH94 Saccharophagus degradans cellobionic acid phosphorylase (CABP) [22]
• GH94 Lachnoclostridium phytofermentans 1,2-β-oligoglucan phosphorylase (LpSOGP) [23]
• GH101 Bifidobacterium longum endo-α-N-acetylgalactosaminidase (EngBF) [24]
• GH112 Bifidobacterium longum galacto-N-biose/lacto-N-biose I phosphorylase (GLNBP) Family First [25]
• GH127 Bifidobacterium longum β-L-arabinofuranosidase (HypBA1) Family First [26]
• GH129 Bifidobacterium bifidum α-N-acetylgalactosaminidase (NagBb) Family First [27]
• GH130 Listeria innocua β-1,2-mannobiose phosphorylase (Lin0857) [28]
• GH136 Bifidobacterium longum lacto-N-biosidase (LnbX) Family First [29]
• GH144 Chitinophaga pinensis endo-β-1,2-glucanase (Cpin_6279) Family First [30]
• PL20 Trichoderma reesei endo-β-1,4-glucuronan lyase (TrGL) Family First [31]
• CBM28 in Clostridium josui Cel5A (CjCBM28) [32]

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16. Ishida T, Fushinobu S, Kawai R, Kitaoka M, Igarashi K, and Samejima M. (2009). Crystal structure of glycoside hydrolase family 55 {beta}-1,3-glucanase from the basidiomycete Phanerochaete chrysosporium. J Biol Chem. 2009;284(15):10100-9. DOI:10.1074/jbc.M808122200 |
20. Hidaka M, Honda Y, Kitaoka M, Nirasawa S, Hayashi K, Wakagi T, Shoun H, and Fushinobu S. (2004). Chitobiose phosphorylase from Vibrio proteolyticus, a member of glycosyl transferase family 36, has a clan GH-L-like (alpha/alpha)(6) barrel fold. Structure. 2004;12(6):937-47. DOI:10.1016/j.str.2004.03.027 |
29. Yamada C, Gotoh A, Sakanaka M, Hattie M, Stubbs KA, Katayama-Ikegami A, Hirose J, Kurihara S, Arakawa T, Kitaoka M, Okuda S, Katayama T, and Fushinobu S. (2017). Molecular Insight into Evolution of Symbiosis between Breast-Fed Infants and a Member of the Human Gut Microbiome Bifidobacterium longum. Cell Chem Biol. 2017;24(4):515-524.e5. DOI:10.1016/j.chembiol.2017.03.012 |