User:Marie-Katherin Zuehlke

All my life I have been interested in environmental issues and thus studied (micro)biology. My PhD thesis was dedicated to the bacterial transformation of bisphenols, which are released from plastics and disrupt the endocrine system (laboratory Frieder Schauer). I focused on the structural elucidation of produced transformation products and their risk assessment. As a Post Doc, I have expanded this by the perspective of bacterial physiology and the proteins involved in degradation processes. Here, I am investigating the bacterial breakdown of algal sugars using proteomics and by detailed functional analysis of specific proteins. I am based at the University of Greifswald, Germany, and Station Biologique de Roscoff, France (teams Thomas Schweder and Mirjam Czjzek).

Please find me on ResearchGate.

Beidler I, Robb CS, Vidal-Melgosa S, Zühlke MK, Bartosik D, Solanki V, Markert S, Becher D, Schweder T, Hehemann JH (2022). Marine bacteroidetes use a conserved enzymatic cascade to digest diatom β-mannan. ISME J.

Dutschei T, Zühlke MK, Welsch N, Eisenack T, Hilkmann M, Krull J, Stühle C, Brott S, Dürwald A, Reisky L, Hehemann JH, Becher, D, Schweder T, Bornscheuer UT (2022). Metabolic engineering enables Bacillus licheniformis to grow on the marine polysaccharide ulvan. Microb. Cell Fact. 21(1): 207.

Dürwald A, Zühlke MK, Schlüter R, Gebbe R, Bartosik D, Unfried F, Becher D, Schweder T (2021). Reaching out in anticipation: bacterial membrane extensions represent a permanent investment in polysaccharide sensing and utilization. Environ. Microbiol. 23: 3149-3163.

Zühlke MK, Schlüter R, Mikolasch A, Henning AK, Giersberg M, Lalk M, Kunze G, Schweder T, Urich T, Schauer F (2020). Biotransformation of bisphenol A analogues by the biphenyl degrading bacterium Cupriavidus basilensis – a structure-biotransformation relationship. Appl. Microbiol. Biotechnol. 104:3569-3583

Reisky L, Préchoux A, Zühlke MK, Bäumgen M, Robb CS, Gerlach N, Roret T, Stanetty C, Larocque R, Michel G, Tao S, Markert S, Unfried F, Mihovilovic MD, Trautwein-Schult A, Becher D, Schweder T, Bornscheuer UT, Hehemann JH (2019). A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan. 12(12):2894-2906. Nature Chem. Biol.

Zühlke MK, Schlüter R, Mikolasch A, Zühlke D, Giersberg M, Schindler H, Henning AK, Frenzel H, Hammer E, Lalk M, Bornscheuer UT, Riedel K, Kunze G, Schauer F (2017). Biotransformation and reduction of estrogenicity of bisphenol A by the biphenyl-degrading Cupriavidus basilensis. Appl. Microbiol. Biotechnol. 101(9):3743-3758.

Zühlke MK, Schlüter R, Henning AK, Lipka M, Mikolasch A, Schumann P, Giersberg M, Kunze G, Schauer F (2016). A novel mechanism of conjugate formation of bisphenol A and its analogues by Bacillus amyloliquefaciens: Detoxification and reduction of estrogenicity of bisphenols. Int. Biodeterior. Biodegrad. 109:165-173.

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1. Beidler I, Robb CS, Vidal-Melgosa S, Zühlke MK, Bartosik D, Solanki V, Markert S, Becher D, Schweder T, and Hehemann JH. (2023). Marine bacteroidetes use a conserved enzymatic cascade to digest diatom β-mannan. ISME J. 2023;17(2):276-285. DOI:10.1038/s41396-022-01342-4 |
2. Zühlke MK, Schlüter R, Mikolasch A, Zühlke D, Giersberg M, Schindler H, Henning AK, Frenzel H, Hammer E, Lalk M, Bornscheuer UT, Riedel K, Kunze G, and Schauer F. (2017). Biotransformation and reduction of estrogenicity of bisphenol A by the biphenyl-degrading Cupriavidus basilensis. Appl Microbiol Biotechnol. 2017;101(9):3743-3758. DOI:10.1007/s00253-016-8061-z |