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Difference between revisions of "Glycoside Hydrolase Family 192"
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== Substrate specificities == | == Substrate specificities == | ||
| − | PgSGL1(H744_1c0224, KEGG) and PgSGL2(H744_2c1936, KEGG) from <i>Photobacterium gaetbulicola</i> and EeSGL1(A0A081KBI6, Uniprot) from <i>Endozoicomonas elysicola</i> are characterized. The three enzymes are specific to β-1,2-glucan among polysaccharides. | + | PgSGL1(H744_1c0224, KEGG) and PgSGL2(H744_2c1936, KEGG) from <i>Photobacterium gaetbulicola</i> and EeSGL1(A0A081KBI6, Uniprot) from <i>Endozoicomonas elysicola</i> are characterized. The three enzymes are specific to β-1,2-glucan among polysaccharides. They hydrolyze β-1,2-glucan endolytically to produce β-1,2-glucooligosaccharides. |
| + | |||
Authors may get an idea of what to put in each field from ''Curator Approved'' [[Glycoside Hydrolase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser window...)'' | Authors may get an idea of what to put in each field from ''Curator Approved'' [[Glycoside Hydrolase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser window...)'' | ||
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== Three-dimensional structures == | == Three-dimensional structures == | ||
| − | + | A ligand-free structure of EeSGL1 is solved in 2025. | |
== Family Firsts == | == Family Firsts == | ||
Revision as of 07:24, 25 February 2026
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
| Glycoside Hydrolase Family GH192 | |
| Clan | GH-S |
| Mechanism | inverting |
| Active site residues | not known |
| CAZy DB link | |
| https://www.cazy.org/GH192.html | |
Substrate specificities
PgSGL1(H744_1c0224, KEGG) and PgSGL2(H744_2c1936, KEGG) from Photobacterium gaetbulicola and EeSGL1(A0A081KBI6, Uniprot) from Endozoicomonas elysicola are characterized. The three enzymes are specific to β-1,2-glucan among polysaccharides. They hydrolyze β-1,2-glucan endolytically to produce β-1,2-glucooligosaccharides.
Authors may get an idea of what to put in each field from Curator Approved Glycoside Hydrolase Families. (TIP: Right click with your mouse and open this link in a new browser window...)
In the meantime, please see these references for an essential introduction to the CAZy classification system: [1, 2].
Kinetics and Mechanism
Content is to be added here.
Catalytic Residues
Content is to be added here.
Three-dimensional structures
A ligand-free structure of EeSGL1 is solved in 2025.
Family Firsts
- First stereochemistry determination
- Content is to be added here.
- First catalytic nucleophile identification
- Content is to be added here.
- First general acid/base residue identification
- Content is to be added here.
- First 3-D structure
- Content is to be added here.
References
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Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. The Biochemist, vol. 30, no. 4., pp. 26-32. DOI:10.1042/BIO03004026.
- Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |