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Difference between revisions of "Template:CBMFamilyPage"
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| − | == | + | == Ligand specificities == |
| − | + | Mention here all major ligand specificities that are found within a given family (also plant or mammalian origin). Certain linkages and promiscuity would also be mentioned here (such as BhCBM6 binding xylobiose and laminarihexaose). | |
| − | == | + | == Structural Features == |
| − | + | ===Fold=== | |
| + | Include here Type A, B, or C, fold (beta trefoil, beta sandwich most likely), | ||
| − | == | + | ===Properties of ligand binding=== |
| − | + | What face of the CBM is the binding pocket located? Side or apex? Include examples pdb codes. important residues for binding (W, Y, F, subsites). Metal ion dependent? | |
| + | |||
| + | == Functionalities == | ||
| + | (delete a subheading when appropriate) | ||
| + | ===Functional role of CBM=== | ||
| + | list here such things like targeting, disruptive, anchoring, proximity/position on substrate. | ||
| + | ===Most Common Associated Catalytic Activity=== | ||
| + | list here GH families, or if family is independent of any catalytic module | ||
| + | ===Additional Associated Modules=== | ||
| + | Examples: Do they exist in duplicate? With another CBM family? FNIII, cohesin, dockerins, etc. | ||
| + | ===Novel Applications=== | ||
| + | Include here if CBM has been used to modify another enzyme, or if a CBM was used to label plant/mammalian tissues? Etc. | ||
| + | |||
| + | == Family Firsts == | ||
| + | ===First Identified=== | ||
| + | insert text here | ||
| + | ===First Structural Characterization=== | ||
| + | insert text here | ||
== References == | == References == | ||
Revision as of 11:36, 4 May 2013
{{UnderConstruction}}
- Author: ^^^Alicia Lammerts van Bueren^^^
- Responsible Curator: ^^^Alicia Lammerts van Bueren^^^
Page content has yet to be added. In the meantime, please see these references for an essential introduction to the CAZy classification system: [1, 2]. CBMs, in particular, have been extensively reviewed [3, 4, 5, 6].
Ligand specificities
Mention here all major ligand specificities that are found within a given family (also plant or mammalian origin). Certain linkages and promiscuity would also be mentioned here (such as BhCBM6 binding xylobiose and laminarihexaose).
Structural Features
Fold
Include here Type A, B, or C, fold (beta trefoil, beta sandwich most likely),
Properties of ligand binding
What face of the CBM is the binding pocket located? Side or apex? Include examples pdb codes. important residues for binding (W, Y, F, subsites). Metal ion dependent?
Functionalities
(delete a subheading when appropriate)
Functional role of CBM
list here such things like targeting, disruptive, anchoring, proximity/position on substrate.
Most Common Associated Catalytic Activity
list here GH families, or if family is independent of any catalytic module
Additional Associated Modules
Examples: Do they exist in duplicate? With another CBM family? FNIII, cohesin, dockerins, etc.
Novel Applications
Include here if CBM has been used to modify another enzyme, or if a CBM was used to label plant/mammalian tissues? Etc.
Family Firsts
First Identified
insert text here
First Structural Characterization
insert text here
References
-
Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. Biochem. J. (BJ Classic Paper, online only). DOI: 10.1042/BJ20080382
- Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |
- Boraston AB, Bolam DN, Gilbert HJ, and Davies GJ. (2004). Carbohydrate-binding modules: fine-tuning polysaccharide recognition. Biochem J. 2004;382(Pt 3):769-81. DOI:10.1042/BJ20040892 |
- Hashimoto H (2006). Recent structural studies of carbohydrate-binding modules. Cell Mol Life Sci. 2006;63(24):2954-67. DOI:10.1007/s00018-006-6195-3 |
- Shoseyov O, Shani Z, and Levy I. (2006). Carbohydrate binding modules: biochemical properties and novel applications. Microbiol Mol Biol Rev. 2006;70(2):283-95. DOI:10.1128/MMBR.00028-05 |
- Guillén D, Sánchez S, and Rodríguez-Sanoja R. (2010). Carbohydrate-binding domains: multiplicity of biological roles. Appl Microbiol Biotechnol. 2010;85(5):1241-9. DOI:10.1007/s00253-009-2331-y |
[[Category:Carbohydrate Binding Module Families|CBMnnn]]