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Difference between revisions of "Polysaccharide Lyase Family 8"
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|{{Hl2}} colspan="2" align="center" |'''Polysaccharide Lyase Family PL8''' | |{{Hl2}} colspan="2" align="center" |'''Polysaccharide Lyase Family PL8''' | ||
|- | |- | ||
| − | | | + | |'''''3D Structure''''' |
| − | |(alpha/alpha)6 barrel + anti-parallel beta-sheet | + | |(alpha/alpha)<sub>6</sub> barrel + anti-parallel beta-sheet |
|- | |- | ||
|'''Mechanism''' | |'''Mechanism''' | ||
| Line 29: | Line 29: | ||
| + | == Known Activities == | ||
| + | hyaluronate lyase (EC 4.2.2.1); chondroitin AC lyase (EC 4.2.2.5); xanthan lyase (EC 4.2.2.12); chondroitin ABC lyase (EC 4.2.2.20). | ||
== Substrate specificities == | == Substrate specificities == | ||
Content is to be added here. | Content is to be added here. | ||
Revision as of 07:22, 5 November 2013
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
- Author: ^^^Michael Suits^^^
- Responsible Curator: ^^^Michael Suits^^^
| Polysaccharide Lyase Family PL8 | |
| 3D Structure | (alpha/alpha)6 barrel + anti-parallel beta-sheet |
| Mechanism | beta-elimination |
| Active site residues | known/not known |
| CAZy DB link | |
| https://www.cazy.org/PL8.html | |
Known Activities
hyaluronate lyase (EC 4.2.2.1); chondroitin AC lyase (EC 4.2.2.5); xanthan lyase (EC 4.2.2.12); chondroitin ABC lyase (EC 4.2.2.20).
Substrate specificities
Content is to be added here.
Authors may get an idea of what to put in each field from Curator Approved Glycoside Hydrolase Families. (TIP: Right click with your mouse and open this link in a new browser window...)
In the meantime, please see these references for an essential introduction to the CAZy classification system: [1, 2].
Kinetics and Mechanism
Content is to be added here.
Catalytic Residues
Content is to be added here.
Three-dimensional structures
Content is to be added here.
Family Firsts
- First stereochemistry determination
- Content is to be added here.
- First catalytic nucleophile identification
- Content is to be added here.
- First general acid/base residue identification
- Content is to be added here.
- First 3-D structure
- Content is to be added here.
References
-
Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. Biochem. J. (BJ Classic Paper, online only). DOI: 10.1042/BJ20080382
- Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |