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Difference between revisions of "Glycoside Hydrolase Family 130"
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== Substrate specificities == | == Substrate specificities == | ||
[[GH130]] contains phosphorylases catalyzing the phosphorolysis of β1-4mannosidic linkage at the non-reducing end of substrates. 4-O-β-D-Mannosyl-D-glucose phosphorylase (EC [{{EClink}}2.4.1.281 2.4.1.281]), β-1,4-mannooligosaccharide phosphorylase(EC [{{EClink}}2.4.1.319 2.4.1.319]), and 1,4-β-mannosyl-N-acetylglucosamine phosphorylase (EC [{{EClink}}2.4.1.320 2.4.1.320]) are members of this family. | [[GH130]] contains phosphorylases catalyzing the phosphorolysis of β1-4mannosidic linkage at the non-reducing end of substrates. 4-O-β-D-Mannosyl-D-glucose phosphorylase (EC [{{EClink}}2.4.1.281 2.4.1.281]), β-1,4-mannooligosaccharide phosphorylase(EC [{{EClink}}2.4.1.319 2.4.1.319]), and 1,4-β-mannosyl-N-acetylglucosamine phosphorylase (EC [{{EClink}}2.4.1.320 2.4.1.320]) are members of this family. | ||
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== Kinetics and Mechanism == | == Kinetics and Mechanism == | ||
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Revision as of 14:47, 23 October 2014
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
- Author: ^^^Wataru Saburi^^^
- Responsible Curator: ^^^Haruhide Mori^^^
| Glycoside Hydrolase Family GH130 | |
| Clan | GH-x |
| Mechanism | retaining/inverting |
| Active site residues | known/not known |
| CAZy DB link | |
| https://www.cazy.org/GH130.html | |
Substrate specificities
GH130 contains phosphorylases catalyzing the phosphorolysis of β1-4mannosidic linkage at the non-reducing end of substrates. 4-O-β-D-Mannosyl-D-glucose phosphorylase (EC 2.4.1.281), β-1,4-mannooligosaccharide phosphorylase(EC 2.4.1.319), and 1,4-β-mannosyl-N-acetylglucosamine phosphorylase (EC 2.4.1.320) are members of this family.
Kinetics and Mechanism
Content is to be added here.
Catalytic Residues
Content is to be added here.
Three-dimensional structures
Content is to be added here.
Family Firsts
- First stereochemistry determination
- Content is to be added here.
- First catalytic nucleophile identification
- Content is to be added here.
- First general acid/base residue identification
- Content is to be added here.
- First 3-D structure
- Content is to be added here.
References
- Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |
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Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. Biochem. J. (BJ Classic Paper, online only). DOI: 10.1042/BJ20080382