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User:Clelton Santos
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Dr Clelton Santos is a Biologist and holds an MS and Ph.D. in Genetics and Molecular Biology. After Postdoc jobs at Cambridge University and the National University of Ireland Galway, He becomes a Research Scientist at the Brazilian Biorenewables National Laboratory National from the Center for Research in Energy and Materials in Campinas, Brazil. His research interests combine structural enzymology and protein engineering for protein discovery and biotechnology application purposes.
He has contributed to structural and functional studies of CAZymes from families GH1 [1, 2] GH54 [ref] GH173 [ref] CBM89 [ref] [3].
- Santos CA, Zanphorlin LM, Crucello A, Tonoli CCC, Ruller R, Horta MAC, Murakami MT, and de Souza AP. (2016). Crystal structure and biochemical characterization of the recombinant ThBgl, a GH1 β-glucosidase overexpressed in Trichoderma harzianum under biomass degradation conditions. Biotechnol Biofuels. 2016;9:71. DOI:10.1186/s13068-016-0487-0 |
- Santos CA, Morais MAB, Terrett OM, Lyczakowski JJ, Zanphorlin LM, Ferreira-Filho JA, Tonoli CCC, Murakami MT, Dupree P, and Souza AP. (2019). An engineered GH1 β-glucosidase displays enhanced glucose tolerance and increased sugar release from lignocellulosic materials. Sci Rep. 2019;9(1):4903. DOI:10.1038/s41598-019-41300-3 |
- Gilbert HJ, Stålbrand H, and Brumer H. (2008). How the walls come crumbling down: recent structural biochemistry of plant polysaccharide degradation. Curr Opin Plant Biol. 2008;11(3):338-48. DOI:10.1016/j.pbi.2008.03.004 |