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Glycoside Hydrolase Family 19
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- Author: ^^^Vincent Eijsink^^^
- Responsible Curator: ^^^Vincent Eijsink^^^
| Glycoside Hydrolase Family GHnn | |
| Clan | GH-x |
| Mechanism | retaining/inverting |
| Active site residues | known/not known |
| CAZy DB link | |
| http://www.cazy.org/fam/GHnn.html | |
Substrate specificities
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Kinetics and Mechanism
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Catalytic Residues
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Three-dimensional structures
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Family Firsts
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First primary sequence determination
Bean leaf chitinase (Broglie et al., 1986)
First stereochemistry determination
Yam chitinase, by NMR (Fukamizo et al., 1995) and Bean chitinase, by HPLC (Iseli et al., 1996)
First general base residue identification
Chitinase from barley; determination by site-directed mutagenesis (Andersen et al., 1997), structural analysis (Hart et al., 1993) and modelling (Brameld and Goddard, 1998). Additional support from structure determination and modelling of a papaya chitinase (Huet et al., 2008).
First general acid residue identification
Chitinase from barley; determination by site-directed mutagenesis (Andersen et al., 1997), structural analysis (Hart et al., 1993) and modelling (Brameld and Goddard, 1998). Additional support from structure determination and modelling of a papaya chitinase (Huet et al., 2008).
First 3-D structure
Barley chitinase (Hart et al., 1993).