Template:CBMFamilyPage

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• Author: ^^^Alicia Lammerts van Bueren^^^
• Responsible Curator: ^^^Alicia Lammerts van Bueren^^^

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Page content has yet to be added. In the meantime, please see these references for an essential introduction to the CAZy classification system: [1, 2]. CBMs, in particular, have been extensively reviewed [3, 4, 5, 6].

Ligand specificities

Mention here all major natural ligand specificities that are found within a given family (also plant or mammalian origin). Certain linkages and promiscuity would also be mentioned here if biologically relevant.

Structural Features

Fold

Structural fold (beta trefoil, beta sandwich, etc.)

Type

Include here Type A, B, or C and properties

Features of ligand binding

Describe CBM binding pocket location (Side or apex) important residues for binding (W, Y, F, subsites), interact with reducing end, non-reducing end, planar surface or within polysaccharide chains. Include examples pdb codes. Metal ion dependent. Etc.

Functionalities

Functional role of CBM

Describe common functional roles such as targeting, disruptive, anchoring, proximity/position on substrate.

Most Common Associated Modules

1. Glycoside Hydrolase Activity

2. Additional Associated Modules (other CBM, FNIII, cohesin, dockerins, expansins, etc.)

Novel Applications

Include here if CBM has been used to modify another enzyme, or if a CBM was used to label plant/mammalian tissues? Etc.

Family Firsts

First Identified

insert text here

First Structural Characterization

insert text here

References

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1. Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. Biochem. J. (BJ Classic Paper, online only). DOI: 10.1042/BJ20080382

[[Category:Carbohydrate Binding Module Families|CBMnnn]]