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We have many unassigned pages in need of Authors and Responsible Curators. See a page that's out-of-date and just needs a touch-up? - You are also welcome to become a CAZypedian. Here's how.
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22 February 2019: Starch-active LPMOs: Glyn Hemsworth recently completed the Auxiliary Activity Family 13 page, which was Curator Approved by Responsible Curator Gideon Davies today. AA13 was first identified in 2014 and is notable as the first lytic polysaccharide mono-oxygenase (LPMO) family that is active on alpha-glycosidic bonds, viz. those in amylose (starch). Overall, LPMOs are an intriguing group of copper-dependent oxidases that open-up insoluble polysaccharide substrates for increased attack by glycoside hydrolases. Read more about AA13 and related beta-glycan-active LPMOs (AA9, AA10, AA11, AA14, & AA15) on their respective CAZypedia pages and at the CAZy Database.
4 February 2019: CAZypedia's first CE page! Today Responsible Curator Michael Suits approved the Carbohydrate Esterase Family 4 page authored by graduate student Alex Anderson, thereby marking a new milestone CAZypedia's history. Carbohydrate Esterases (CEs) catalyze the de-O-acylation or de-N-acylation of saccharides (the latter are formally amidases), and CE4 contains members with either activity, e.g. acetylxylan esterases and peptidoglycan deacetylases. CE4 members thus play diverse biological roles in nature. Learn more about the structure and mechanism of these metal-dependent de-acylases here.
27 November 2018: Remember, remember... an end of November new CAZypedia CBM family page. The type C L-rhamnose binding CBM67 family is now on-line in CAZypedia. Satoshi Kaneko authored the page and Harry Gilbert acted as responsible curator. Learn more about the structure and function of the CBM67 family on its CAZypedia page.
23 November 2018: Welcome to the CAZypedia fold CBM49! The crystalline cellulose-binding CBM49 CAZypedia page was authored by Breeanna Urbanowicz and Elizabeth Ficko-Blean. Breeanna Urbanowicz also acted as responsible curator. There is experimental evidence that rice CBM49 is cleaved post-translationally in vivo which probably plays an important role in plant growth. Find out more about the functionally interesting family 49 CBMs here.