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User:Florence Vincent
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From 1998 to 2001, I did my PhD in the group of Christian Cambillau in Marseille working on the structure-function relationships of several mammalian odorant binding proteins (OBPs). In January 2002 I joined the group of Gideon Davies in the YSBL laboratory (York Structural Biology laboratory) as a postdoctoral fellow to study various carbohydrate esterases and their role in bacterial cell wall formation and breakdown. We worked on family CE4, CE9, and also GH5 as well as other carbohydrate active enzyme like NagA from Bacillus subtilis a glucosamine-6-phophate deacetylase and NagB a frustose-6-phosphate isomerase.
I return to Marseille in 2004 to join the group of structural glycobiology directed by Yves Bourne. Since then I’ve been interested in a GH73, an isoprenoid binding module appended to a CBM2 and possibly involved in oxydoreduction events during plant cell wall breakdown; two putative carbohydrate binding domain appended two global regulators as well as several GT2 and GT4, all involved in biofilm formation in Pseudomonas aeruginosa