Auxiliary Activity Family 10

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• Author: ^^^Vincent Eijsink^^^ and ^^^Gustav Vaaje-Kolstad^^^
• Responsible Curator: ^^^Vincent Eijsink^^^

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Auxiliary Activity Family 10
Clan	none, structurally related to AA9
Mechanism	lytic oxidase
Active site residues	mononuclear copper ion
CAZy DB link
https://www.cazy.org/AA10.html

Substrate specificities

Content is to be added here. In the meantime, please see these references for an essential introduction to the CAZy classification system: [1, 2].

Kinetics and Mechanism

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Catalytic Residues

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Three-dimensional structures

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Family Firsts

First stereochemistry determination

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First catalytic nucleophile identification

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First general acid/base residue identification

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First 3-D structure

CBP21, the single AA10-type LPMO from the Gram negative bacterium Serratia marcescens. Entry in the protein data bank: [1]

References

1. Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. Biochem. J. (BJ Classic Paper, online only). DOI: 10.1042/BJ20080382

2. Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |