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User:Alex Anderson
Alex Anderson recieved his BScH from Wilfrid Laurier University (Canada) in 2017, and began his foray into microbiology as a diagnostic laboratory technician at the Public Health Ontario Laboratories where he became fascinated with microbial cell surface structure and function. Alex completed his MSc in 2019 the lab of Dr. ^^^Joel Weadge^^^, alongside ^^^Michael Suits^^^, at WLU where he studied the structure and function of CAZymes responsible for the biosynthesis, modification and export of cellulosic materials involved in biofilm formation in Gram-negative pathogens. Alex is currently a PhD candidate in the lab of Dr. ^^^Anthony Clarke^^^ at the University of Guelph where he studies the mechanism of peptidoglycan O-acetylation in Gram-negative bacteria.
Alex and colleagues have demonstrated the structures of:
CAZy-unclassified Escherichia coli phosphoethanolamine transferase BcsG (6PCZ/6PD0) [1]
GH5 Clostridioides difficile endo-β-glucanase CcsZ (6UJE/6UJF) [2]
- Anderson AC, Burnett AJN, Hiscock L, Maly KE, and Weadge JT. (2020). The Escherichia coli cellulose synthase subunit G (BcsG) is a Zn(2+)-dependent phosphoethanolamine transferase. J Biol Chem. 2020;295(18):6225-6235. DOI:10.1074/jbc.RA119.011668 |
- Scott W, Lowrance B, Anderson AC, and Weadge JT. (2020). Identification of the Clostridial cellulose synthase and characterization of the cognate glycosyl hydrolase, CcsZ. PLoS One. 2020;15(12):e0242686. DOI:10.1371/journal.pone.0242686 |