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File:EXT1EXT2 GT47 structure rendering figure 2 V3.pdf

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EXT1EXT2_GT47_structure_rendering_figure_2_V3.pdf(file size: 1.26 MB, MIME type: application/pdf)

Figure 2: GT47 Domain of EXT1 in EXT1-2 Heterocomplex

A) Cartoon representation of EXT1 (Salmon and Green) and EXT2 (Gray) in the EXT1-2 heparan sulfate co-polymerase heterocomplex. The GT47 domain of EXT1 is highlighted in green, while the remaining GT47 domain is highlighted in salmon. The nucleotide bound to the active site shown is shown in pink, and the 4-mer heparan sulfate oligosaccharide acceptor is shown in cyan. B) Enlargement of the GT47 domain in EXT1, highlighting the two Rossman folds of the GT-B glycosyltransferase domain (β-strands of N-Term and C-Term Rossman Folds shown in yellow).

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current08:21, 26 June 2024 (1.26 MB)Daniel Tehrani (talk | contribs)

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