Glycoside Hydrolase Family 14

CAZypedia needs your help: This page is currently lacking a Responsible Curator and one or more Authors. If you are an expert on this family and would like to help us improve CAZypedia by getting involved with writing and maintaining this page, please contact the Primary Curator.

Undergraduate students, (post)graduate students, post-doctoral researchers, research associates, and professors are all welcomed to contribute!

• If you are interested in contributing to CAZypedia, please see the 10th anniversary publication [1] and this page for an overview of the content and mission of our community-driven resource. Future authors of CAZypedia can include the CAZypedia article [1] and cite individual pages in their curricula vitae to reflect their contribution.
• Until this CAZypedia page is completed, current information on the composition of this family is available via the corresponding page of the CAZy database [2]:
  https://www.cazy.org/GH14.html

References

1. CAZypedia Consortium (2018). Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes. Glycobiology. 2018;28(1):3-8. DOI:10.1093/glycob/cwx089 |
2. Drula E, Garron ML, Dogan S, Lombard V, Henrissat B, and Terrapon N. (2022). The carbohydrate-active enzyme database: functions and literature. Nucleic Acids Res. 2022;50(D1):D571-D577. DOI:10.1093/nar/gkab1045 |

• Author:
• Responsible Curator:

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Glycoside Hydrolase Family GH14
Clan	none
Mechanism	inverting
Active site residues	known
CAZy DB link
https://www.cazy.org/GH14.html

Substrate specificities

Content is to be added here. In the meantime, please see these references for an essential introduction to the CAZy classification system: [3, 4].

Kinetics and Mechanism

Content is to be added here.

Catalytic Residues

Content is to be added here.

Three-dimensional structures

Content is to be added here.

Family Firsts

First stereochemistry determination

Content is to be added here.

First catalytic nucleophile identification

Content is to be added here.

First general acid/base residue identification

Content is to be added here.

First 3-D structure

Content is to be added here.

References

3. Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. Biochem. J. (BJ Classic Paper, online only). DOI: 10.1042/BJ20080382

4. Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |