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Glycoside Hydrolase Family 101
| Glycoside Hydrolase Family GH101 | |
| Clan | GH-x |
| Mechanism | retaining |
| Active site residues | known |
| CAZy DB link | |
| http://www.cazy.org/fam/GH101.html | |
Substrate specificities
Gal-beta-1,3-GalNAc-alpha-R O-linked glycans on proteins
Kinetics and Mechanism
Retaining mechanism determined by NMR with the BlGH101 enzyme.
Catalytic Residues
Nucleophile SpGH101 D764 Acid/base catalyst SpGH101 E796
Three-dimensional structures
Family Firsts
- First sterochemistry determination
- Cite some reference here, with a short explanation [1].
- First catalytic nucleophile identification
- First general acid/base residue identification
- First 3-D structure