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Glycoside Hydrolase Family 112

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Glycoside Hydrolase Family 112
Clan none
Mechanism inverting
Active site residues known
CAZy DB link
http://www.cazy.org/fam/GH112.html

Substrate specificities

Kinetics and Mechanism

Catalytic Residues

Three-dimensional structures

Family Firsts

First sterochemistry determination
First catalytic nucleophile identification
First general acid/base residue identification
First 3-D structure
Cite some reference here, with a short explanation [1].

References

  1. Hidaka M, Nishimoto M, Kitaoka M, Wakagi T, Shoun H, and Fushinobu S. (2009). The crystal structure of galacto-N-biose/lacto-N-biose I phosphorylase: a large deformation of a TIM barrel scaffold. J Biol Chem. 2009;284(11):7273-83. DOI:10.1074/jbc.M808525200 | PubMed ID:19124470 [REF1]