Polysaccharide Lyase Family 34

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• Author: Marie-Line Garron
• Responsible Curator: Marie-Line Garron

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Polysaccharide Lyase Family PL33
3D Structure
Mechanism
Charge neutraliser
Active site residues
CAZy DB link
https://www.cazy.org/PL34.html

Substrate specificities

PL34 is a small family (28 sequences), mainly bacterial, with only one sequence belonging to the metazoan Knipowitschia caucasica. The founding member of family 34, and the only one characterized, belongs to OPIT5_18480 of Opitutaceae bacterium TAV5 (AHF91913.1). This enzyme presents an activity against alginate (EC 4.2.2.-) [1].

Kinetics and Mechanism

Not determined

Catalytic Residues

Not determined

Three-dimensional structures

Unsolved

Family Firsts

First description of catalytic activity

Alginate lyase was the first activity discovered for the family PL34 [1].

First First charge neutralizer identification

To be determined

First Brønstead acid and base residue identification

To be determined

First 3-D structure

To be determined

References

1. Helbert W, Poulet L, Drouillard S, Mathieu S, Loiodice M, Couturier M, Lombard V, Terrapon N, Turchetto J, Vincentelli R, and Henrissat B. (2019). Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space. Proc Natl Acad Sci U S A. 2019;116(13):6063-6068. DOI:10.1073/pnas.1815791116 |