User:Lauren McKee

I hold the position of Researcher with Docent (Reader/Associate Prof-equivalent) in Biotechnology at the KTH Division of Glycoscience in Stockholm, Sweden. I am principal investigator for the Stockholm CAZyme group. And, since January 2023, I am a vice-director for a national PhD Academy in Sweden, financed by the Wallenberg Wood Science Centre network. I studied for my Biochemistry BSc, Environmental Biogeochemistry MSc, and Carbohydrate Enzymology PhD in my home town, at Newcastle University, UK. My doctoral research focussed on structure-function analysis of GH43 enzymes [1] [2] and was supervised by Professor Harry Gilbert. I spent almost two years with Harry at the Complex Carbohydrate Research Centre at UGA, Georgia, USA. Shortly after completing my PhD, I moved to Stockholm to begin a post-doctoral scholarship position supervised by Professor Harry Brumer [3] [4], before he moved to UBC in Canada. When Harry moved, I worked with Prof Vincent Bulone [5] [6] until I secured my own independent funding and could begin to run my own team and projects. My main interests are the discovery and characterisation of glycoside hydrolases, glycosyltransferases, polysaccharide utilisation loci [7] [8], and carbohydrate binding modules (especially family CBM92 [9]), with a particular focus on environmental bacteria from soil, marine, and industrial ecosystems [10] [11].

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2. McKee LS, Peña MJ, Rogowski A, Jackson A, Lewis RJ, York WS, Krogh KB, Viksø-Nielsen A, Skjøt M, Gilbert HJ, and Marles-Wright J. (2012). Introducing endo-xylanase activity into an exo-acting arabinofuranosidase that targets side chains. Proc Natl Acad Sci U S A. 2012;109(17):6537-42. DOI:10.1073/pnas.1117686109 |
3. Larsbrink J, Rogers TE, Hemsworth GR, McKee LS, Tauzin AS, Spadiut O, Klinter S, Pudlo NA, Urs K, Koropatkin NM, Creagh AL, Haynes CA, Kelly AG, Cederholm SN, Davies GJ, Martens EC, and Brumer H. (2014). A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes. Nature. 2014;506(7489):498-502. DOI:10.1038/nature12907 |