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User:Mirjam Czjzek

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This is the user page of Mirjam Czjzek. I am a permanent researcher of the french national research center "CNRS" (Centre National de Recherche Scientifique), and I am working at the Marine Station "Station Biologique de Roscoff", France.

I am crystallographer by education and have discovered the world of CAZymes by working on crystal structures of cellulases and beta-glucosidases for several years in the group of Bernard Henrissat in Marseille, France. In 2005 I moved to the Station Biologique de Roscoff, where my research program entitled "marine glycobiology" currently focuses on the structures and functions of carbohydrate-active enzymes, including their CBMs, which are involved in marine algal cell wall polysaccharide depolymerization. We are actually exploring the genome data of the marine bacterium "Zobellia galactanivorans" hunting for new families and/or enzymes with new substrate specificites. We use medium throughput heterologous protein expression followed by enzymology, liquid chromatography, FACE gels, SAXS and crystallography for the biochemical and structural characterization of CAZymes.