Polysaccharide Lyase Family 34

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• Author: Marie-Line Garron
• Responsible Curator: Marie-Line Garron

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Polysaccharide Lyase Family PL33
3D Structure
Mechanism
Charge neutraliser
Active site residues
CAZy DB link
http://www.cazy.org/PL33.html

Substrate specificities

PL34 is a small family (28 sequences), mainly bacterial, with only one sequence belonging to the metazoan Knipowitschia caucasica (PL34)[1]. The founding member of family 34, and the only one characterized, belongs to OPIT5_18480 of Opitutaceae bacterium TAV5 (AHF91913.1). This enzyme presents an activity against alginate (EC 4.2.2.-) [2].

Kinetics and Mechanism

Not determined

Catalytic Residues

Not determined

Three-dimensional structures

Unsolved

Family Firsts

First description of catalytic activity

Alginate lyase was the first activity discovered for the family PL34 [2].

First First charge neutralizer identification

To be determined

First Brønstead acid and base residue identification

To be determined

First 3-D structure

To be determined

References

1. Drula E, Garron ML, Dogan S, Lombard V, Henrissat B, and Terrapon N. (2022). The carbohydrate-active enzyme database: functions and literature. Nucleic Acids Res. 2022;50(D1):D571-D577. DOI:10.1093/nar/gkab1045 |
2. Helbert W, Poulet L, Drouillard S, Mathieu S, Loiodice M, Couturier M, Lombard V, Terrapon N, Turchetto J, Vincentelli R, and Henrissat B. (2019). Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space. Proc Natl Acad Sci U S A. 2019;116(13):6063-6068. DOI:10.1073/pnas.1815791116 |