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Difference between revisions of "User:Zachary Armstrong"
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[[Image:Z_Armstrong.png|200px|right]] | [[Image:Z_Armstrong.png|200px|right]] | ||
| − | Dr. Zachary Armstrong, a native of Iqaluit, Nunavut, obtained his B.Sc. — majoring in chemistry and biochemistry — from the [https://www.ubc.ca/ University of British Columbia]. His final year project, performed under the guidance of Professor [[User:Steve Withers|Steve Withers]], focused on the creation of a [[GH11]] thioglycoligase <cite>Armstrong2010</cite>. He completed his PhD at the University of British Columbia, co-supervised by Professors | + | Dr. Zachary Armstrong, a native of Iqaluit, Nunavut, obtained his B.Sc. — majoring in chemistry and biochemistry — from the [https://www.ubc.ca/ University of British Columbia]. His final year project, performed under the guidance of Professor [[User:Steve Withers|Steve Withers]], focused on the creation of a [[GH11]] thioglycoligase <cite>Armstrong2010</cite>. He completed his PhD at the University of British Columbia, co-supervised by Professors Steve Withers and [http://hallam.microbiology.ubc.ca/ Steven J. Hallam]. This work focused on the identification of glycoside hydrolases from metagenomic sources — including the beaver gut<cite>Armstrong2018</cite>,a mining bioreactor<cite>Armstrong2013</cite> and soils<cite>Armstrong2019mSys</cite>— and the engineering of glycosynthases from metagenomes and synthetic gene libraries<cite>Armstrong2019Acs</cite>. In 2018 he joined the group of [[User:Gideon Davies|Gideon Davies]] in the [https://www.york.ac.uk/chemistry/research/ysbl/ York Structural Biology Laboratories] at the [https://www.york.ac.uk/ University of York] as a postdoctoral research associate. His current work focuses on mechanism-based inhibitors and activity-based protein profiling of human carbohydrate processing enzymes. |
He has determined the crystal structure of : | He has determined the crystal structure of : | ||
* [[GH164]] ''Bacteroides salyersiae'' beta-mannosidase <cite>Armstrong2019JBC</cite> | * [[GH164]] ''Bacteroides salyersiae'' beta-mannosidase <cite>Armstrong2019JBC</cite> | ||
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#Armstrong2010 pmid=20112321 | #Armstrong2010 pmid=20112321 | ||
#Armstrong2018 pmid=30013164 | #Armstrong2018 pmid=30013164 | ||
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#Armstrong2019mSys pmid=31164449 | #Armstrong2019mSys pmid=31164449 | ||
#Armstrong2013 pmid=23906845 | #Armstrong2013 pmid=23906845 | ||
| − | + | #Armstrong2019Acs Armstrong Z, Liu F, Chen H-M, Hallam SJ, Withers SG. (2019) Systematic Screening of Synthetic Gene-Encoded Enzymes for Synthesis of Modified Glycosides. ''ACS Catal''. 53, 689-98. | [https://doi.org/10.1021/acscatal.8b05179 DOI: 10.1021/acscatal.8b05179] | |
| − | #Armstrong2019Acs doi | ||
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#Armstrong2019JBC pmid=31871050 | #Armstrong2019JBC pmid=31871050 | ||
Latest revision as of 07:58, 2 April 2020
Dr. Zachary Armstrong, a native of Iqaluit, Nunavut, obtained his B.Sc. — majoring in chemistry and biochemistry — from the University of British Columbia. His final year project, performed under the guidance of Professor Steve Withers, focused on the creation of a GH11 thioglycoligase [1]. He completed his PhD at the University of British Columbia, co-supervised by Professors Steve Withers and Steven J. Hallam. This work focused on the identification of glycoside hydrolases from metagenomic sources — including the beaver gut[2],a mining bioreactor[3] and soils[4]— and the engineering of glycosynthases from metagenomes and synthetic gene libraries[5]. In 2018 he joined the group of Gideon Davies in the York Structural Biology Laboratories at the University of York as a postdoctoral research associate. His current work focuses on mechanism-based inhibitors and activity-based protein profiling of human carbohydrate processing enzymes.
He has determined the crystal structure of :
Error fetching PMID 30013164:
Error fetching PMID 31164449:
Error fetching PMID 23906845:
Error fetching PMID 31871050:
- Error fetching PMID 20112321:
- Error fetching PMID 30013164:
- Error fetching PMID 23906845:
- Error fetching PMID 31164449:
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Armstrong Z, Liu F, Chen H-M, Hallam SJ, Withers SG. (2019) Systematic Screening of Synthetic Gene-Encoded Enzymes for Synthesis of Modified Glycosides. ACS Catal. 53, 689-98. | DOI: 10.1021/acscatal.8b05179
- Error fetching PMID 31871050: