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Difference between revisions of "Polysaccharide Lyase Family 34"
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| − | * [[Author]]: | + | * [[Author]]: [[User:Marie-Line Garron|Marie-Line Garron]] |
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== Substrate specificities == | == Substrate specificities == | ||
| − | + | PL34 is a small family (28 sequences), mainly bacterial, with only one sequence belonging to the metazoan ''Knipowitschia caucasica'' ([http://www.cazy.org/PL34.html PL34])<cite>Drula2022</cite>. The founding member of family 34, and the only one characterized, belongs to OPIT5_18480 of Opitutaceae bacterium TAV5 (AHF91913.1). This enzyme presents an activity against alginate (EC 4.2.2.-) <cite>Helbert2019</cite>. | |
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== Kinetics and Mechanism == | == Kinetics and Mechanism == | ||
| − | + | Not determined | |
== Catalytic Residues == | == Catalytic Residues == | ||
| − | + | Not determined | |
== Three-dimensional structures == | == Three-dimensional structures == | ||
| − | + | Unsolved | |
== Family Firsts == | == Family Firsts == | ||
| − | ;First | + | ;First description of catalytic activity: Alginate lyase was the first activity discovered for the family PL34 <cite>Helbert2019</cite>. |
| − | ;First | + | ;First First charge neutralizer identification: To be determined |
| − | ;First | + | ;First Brønstead acid and base residue identification: To be determined |
| − | ;First 3-D structure: | + | ;First 3-D structure: To be determined |
== References == | == References == | ||
<biblio> | <biblio> | ||
| − | # | + | #Drula2022 pmid=34850161 |
| − | # | + | #Helbert2019 pmid=30850540 |
</biblio> | </biblio> | ||
| − | [[Category: | + | [[Category:Polysaccharide Lyase Families|PL034]] |
Latest revision as of 08:32, 23 August 2024
This page has been approved by the Responsible Curator as essentially complete. CAZypedia is a living document, so further improvement of this page is still possible. If you would like to suggest an addition or correction, please contact the page's Responsible Curator directly by e-mail.
| Polysaccharide Lyase Family PL33 | |
| 3D Structure | |
| Mechanism | |
| Charge neutraliser | |
| Active site residues | |
| CAZy DB link | |
| http://www.cazy.org/PL33.html | |
Substrate specificities
PL34 is a small family (28 sequences), mainly bacterial, with only one sequence belonging to the metazoan Knipowitschia caucasica (PL34)[1]. The founding member of family 34, and the only one characterized, belongs to OPIT5_18480 of Opitutaceae bacterium TAV5 (AHF91913.1). This enzyme presents an activity against alginate (EC 4.2.2.-) [2].
Kinetics and Mechanism
Not determined
Catalytic Residues
Not determined
Three-dimensional structures
Unsolved
Family Firsts
- First description of catalytic activity
- Alginate lyase was the first activity discovered for the family PL34 [2].
- First First charge neutralizer identification
- To be determined
- First Brønstead acid and base residue identification
- To be determined
- First 3-D structure
- To be determined
References
- Drula E, Garron ML, Dogan S, Lombard V, Henrissat B, and Terrapon N. (2022). The carbohydrate-active enzyme database: functions and literature. Nucleic Acids Res. 2022;50(D1):D571-D577. DOI:10.1093/nar/gkab1045 |
- Helbert W, Poulet L, Drouillard S, Mathieu S, Loiodice M, Couturier M, Lombard V, Terrapon N, Turchetto J, Vincentelli R, and Henrissat B. (2019). Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space. Proc Natl Acad Sci U S A. 2019;116(13):6063-6068. DOI:10.1073/pnas.1815791116 |