CAZypedia needs your help!
We have many unassigned pages in need of Authors and Responsible Curators. See a page that's out-of-date and just needs a touch-up? - You are also welcome to become a CAZypedian. Here's how.
Scientists at all career stages, including students, are welcome to contribute.
Learn more about CAZypedia's misson here and in this article.
 Totally new to the CAZy classification? Read this first.

Difference between revisions of "Template:News"

From CAZypedia
Jump to navigation Jump to search
m (added Curator Approved link)
 
(192 intermediate revisions by 2 users not shown)
Line 1: Line 1:
−
'''14 February 2020:''' ''A rose by any other name would smell as sweet.'' The human gut bacterium ''Roseburia intestinalis'' provides a curator approved [[Carbohydrate Binding Module Family 86]] page as a special Valentine Day's gift. [[CBM86]] members have only been described at the N-termini of [[GH10]] xylananses. ''Roseburia intestinalis'' certainly enjoys the sugary xylans it encounters in the dietary tract as a carbon source and likely uses the [[CBM86]] modules to enhance xylan capture through improved xylan affinity for the xylanase enzymes.  The [[CBM86]] page was written in record time by '''[[User:Maria Louise Leth|Maria Louise Leth]]''' with '''[[User:Maher Abou Hachem|Maher Abou Hachem]]''' acting as responsible curator. Read more on the ''rosy'' xylan-binding [[CBM86]] family [[CBM86|here]]. 
+
'''1 November 2024:''' ''Is this a world record? Six CAZypedia families in one fell swoop!'' The '''[[CBM47]], [[CBM70]], [[CBM96]], [[CBM105]], [[CBM106]] and [[PL44]]''' ''CAZypedia'' pages are now flipped to [[Curator Approved]] status. What do these diverse families from diverse origins with diverse binding specificities have in common?  Astonishingly, at least one characterized member from each family interacts with a charged glycan! '''[[User:Wenwen Tao|Wenwen Tao]]''' authored the [[CBM47]], [[CBM96]] and [[CBM106]] pages, '''[[User:Menghui Sun|Menghui Sun]]''' authored the [[CBM70]] page, '''[[User:Guanchen Liu|Guanchen Liu]]''' authored the [[CBM105]] page and '''[[User:Jinhang Zhou|Jinhang Zhou]]''' authored the [[PL44]] page.  All this under the responsible curatorship of '''[[User:Yaoguang Chang|Yaoguang Chang]]'''. ''Dive into these diverse families on their respective ''CAZypedia'' pages: '''[[CBM47]], [[CBM70]], [[CBM96]], [[CBM105]], [[CBM106]] and [[PL44]]!'''''
−
 
+
------
−
'''16 December 2019:''' ''Closing the year with marine CAZymes:'' The '''[[Glycoside Hydrolase Family 107]]''' page, which describes a family of endo-1,4-fucanases, was finalized today by [[Author]] '''[[User:David Teze|David Teze]]''' and [[Responsible Curator]] '''[[User:Al Boraston|Alisdair Boraston]]'''.  The characterized enzymes of this family hydrolyze the marine polysaccharides known as fucoidans (sulfated fucans).  First identified by the Roscoff group in 2006 (see ''e.g.'' [[User:Gurvan Michel|Gurvan Michel]] and [[User:Mirjam Czjzek|Mirjam Czjzek]]), recent collaborative work by the [[User:Steve Withers|Withers]] and [[User:Al Boraston|Boraston]] groups has resolved the structure and mechanism of '''[[GH107]]'''.  Of particular note, crystallography of two '''[[GH107]]''' members has revealed similarity with [[GH29]] members, which together now form the new [[Clan]] GH-R.  ''See the '''[[GH107]]''' page for the details from the seminal publications on this family!''
+
'''25 October 2024:''' ''Laminariawesome!'' Check out two new marine families of CBMs, '''[[CBM102]]''' and '''[[CBM103]]''', now on ''CAZypedia'' which have an ecological role in bacterial degradation of laminarin during phytoplankton blooms.  Some function as surface glycan binding proteins but others have roles in targeting their appended catalytic modules to substrate.  Both pages were [[author]]ed by '''[[User:Marie-Katherin Zuehlke|Marie-Katherin Zühlke]]'''. ''Read up on these environmentally important CBMs on their respective [[CBM102]] and [[CBM103]] pages!''
 +
----
 +
'''19 July 2024:''' ''Chalk-up one more for the GTs!'' The '''[[Glycosyltransferase Family 47]]''' page joined the small group of [[Curator Approved]] [[Glycosyltransferase Families]] pages in ''CAZypedia'' today. This entry was [[author]]ed by Ph.D. students '''[[User:Daniel Tehrani|Daniel Tehrani]]''' and '''[[User:Charlie Corulli|Charlie Corulli]]''', and [[Responsible Curator|Curated]] by '''[[User:Breeanna Urbanowicz|Breeanna Urbanowicz]]''' with input from '''[https://ccrc.uga.edu/team/kelley-moremen/ Kelley Moremen]'''.  Widely represented in plants, '''[[GT47]]''' members are anomer-[[inverting]] [[glycosyltransferases]], which are involved in the biosynthesis of several cell wall matrix polysaccharides.  Representatives from mammals are involved in heparin biosynthesis.  Correspondingly, members of [[GH47]] have diverse substrate specificities, including the transfer of both anionic and neutral monosaccharides to polysaccharides.  ''This is a great example where two keen Ph.D. students worked with their supervisors to create a valuable page for the scientific community. We encourage others to follow their lead, on your favorite family!''
 
----
 
----
−
'''Friday the 13th of December 2019:''' ''A spooky Christmas gift:'' The bacterial [[CBM71]] family is a new addition to [[Carbohydrate Binding Module Families|CAZypedia CBM]] just in time for Christmas!  The CAZypedia CBM page describes the characterization of two lactose- and lacNAc- binding Pneumococcal [[CBM71]] members. The page was authored by '''[[User:Ben Pluvinage|Ben Pluvinage]]''' with '''[[User:Al Boraston|Alisdair Boraston]]''' acting as responsible curator.   ''Find out more on the [[CBM71]] family [[CBM71|here]]!''  
+
'''9 July 2024:''' ''Yet another new family of beta-1,2-glucan-active enzymes!'' Today, '''[[User:Masahiro Nakajima|Masahiro Nakajima]]''' [[Curator Approved]] the '''[[Glycoside Hydrolase Family 186]]''' page by '''[[User:Sei Motouchi|Sei Motouchi]]'''. '''[[GH186]]''' is a family of anomer-[[inverting]] enzymes from bacteria, members of which are specific for beta-1,2-glucans.  Intriguingly, although some [[GH186]] members work as classic [[glycoside hydrolases]], others perform transglycosylation by wrapping the sugar chain around in the active-site, to position the 6-OH group of a terminal glucosyl unit for direct attack.  Also notable, [[GH186]] members appear to use an extended chain of water molecules to relay acceptor deprotonation by the [[general base]] residue, ''i.e.'' a [https://en.wikipedia.org/wiki/Grotthuss_mechanism Grotthuss mechanism]. ''Check out the '''[[GH186]]''' page to learn more about these interesting enzymes, and make sure to see the [[GH189]], [[GH144]], and [[GH162]] pages from this same group.''
  
 
----
 
----
−
'''3 November 2019:''' ''Xylan-cleaving LPMOs:'' Today, [[Responsible Curator]] '''[[User:Jean-Guy Berrin|Jean-Guy Berrin]]''' approved the '''[[Auxiliary Activity Family 14]]''' page [[Author|authored]] by '''[[User:Marie Couturier|Marie Couturier]]''', which describes one of the newer families of lytic polysaccharide monooxygenases (LPMOs) described in the CAZy database. '''[[AA14]]''' was first described in 2018 by '''[[User:Marie Couturier|Marie]]''', '''[[User:Jean-Guy Berrin|Jean-Guy]]''', and their co-workers. Notably, they showed that the founding members of this family were specific for the plant cell wall matrix glycan, xylan, which contrasts other families of LPMOs that are predominantly cellulose- or chitin-active. ''Check out the '''[[AA14]]''' page for more details!''
+
'''2 May 2024:''' ''CBDs I to X... A major milestone!'' '''CBM families 1 to 10 are now complete!''' These are the old CBD (cellulose-binding domain) families, which used to have roman numerals as part of their nomenclature. A special thank you to all the authors and responsible curators who have contributed to this major milestone. Go have a peek at each of these old-school families on their respective ''CAZypedia'' pages: '''[[CBM1]], [[CBM2]], [[CBM3]], [[CBM4]], [[CBM5]], [[CBM6]], [[CBM7]], [[CBM8]], [[CBM9]], and [[CBM10]]'''.
−
----
 
−
'''24 October 2019:''' ''A tale of an amoebal CBM:'' The '''[[Carbohydrate Binding Module Family 55]]''' page discussing the pathogenically interesting chitin-binding '''[[CBM55]]''' family has been flipped to curator approved. The '''[[CBM55]]''' family was first identified from ''Entamoeba histolytica'', a protist that causes dysentery and liver abscesses.  The page was authored by '''[[User:John Samuelson|John Samuelson]]''' with  '''[[User:Elizabeth Ficko-Blean|Elizabeth Ficko-Blean]]''' acting as responsible curator.  ''Read more on this amoebal CBM family on the '''[[CBM55]]''' page.''
 
−
----
 
−
'''15 October 2019:''' ''A new debut for beta(1-2):'' The '''[[Glycoside Hydrolase Family 144]]''' page, which describes the β-1,2-glucanases in this family, was completed by [[Author]] '''[[User:Koichi Abe|Koichi Abe]]''' and [[Responsible Curator]] '''[[User:Masahiro Nakajima|Masahiro Nakajima]]''' today. '''[[GH144]]''' was founded in 2017 based on a seminal publication by '''[[User:Koichi Abe|Koichi Abe]]''', '''[[User:Masahiro Nakajima|Masahiro Nakajima]]''', and their colleagues.  Interestingly,  '''[[GH144]]''' contains both ''endo''-β-1,2-glucanases ([{{EClink}}3.2.1.71 EC 3.2.1.71]), as well as ''exo''-acting enzymes that release sophorose (Glc-β(1,2)-Glc) from the nonreducing end of β(1,2)-glucan chains ("sophorohydrolases", analogous to the more well-known "cellobiohydrolases") ''Learn more about these enzymes, whose protein structure is distantly related to that of the fungal β-1,2-glucanases from [[GH162]], on the '''[[GH144]]''' page!''
 
 
----
 
----

Latest revision as of 16:03, 21 November 2024

1 November 2024: Is this a world record? Six CAZypedia families in one fell swoop! The CBM47, CBM70, CBM96, CBM105, CBM106 and PL44 CAZypedia pages are now flipped to Curator Approved status. What do these diverse families from diverse origins with diverse binding specificities have in common? Astonishingly, at least one characterized member from each family interacts with a charged glycan! Wenwen Tao authored the CBM47, CBM96 and CBM106 pages, Menghui Sun authored the CBM70 page, Guanchen Liu authored the CBM105 page and Jinhang Zhou authored the PL44 page. All this under the responsible curatorship of Yaoguang Chang. Dive into these diverse families on their respective CAZypedia pages: CBM47, CBM70, CBM96, CBM105, CBM106 and PL44!

25 October 2024: Laminariawesome! Check out two new marine families of CBMs, CBM102 and CBM103, now on CAZypedia which have an ecological role in bacterial degradation of laminarin during phytoplankton blooms. Some function as surface glycan binding proteins but others have roles in targeting their appended catalytic modules to substrate. Both pages were authored by Marie-Katherin Zühlke. Read up on these environmentally important CBMs on their respective CBM102 and CBM103 pages!

19 July 2024: Chalk-up one more for the GTs! The Glycosyltransferase Family 47 page joined the small group of Curator Approved Glycosyltransferase Families pages in CAZypedia today. This entry was authored by Ph.D. students Daniel Tehrani and Charlie Corulli, and Curated by Breeanna Urbanowicz with input from Kelley Moremen. Widely represented in plants, GT47 members are anomer-inverting glycosyltransferases, which are involved in the biosynthesis of several cell wall matrix polysaccharides. Representatives from mammals are involved in heparin biosynthesis. Correspondingly, members of GH47 have diverse substrate specificities, including the transfer of both anionic and neutral monosaccharides to polysaccharides. This is a great example where two keen Ph.D. students worked with their supervisors to create a valuable page for the scientific community. We encourage others to follow their lead, on your favorite family!

9 July 2024: Yet another new family of beta-1,2-glucan-active enzymes! Today, Masahiro Nakajima Curator Approved the Glycoside Hydrolase Family 186 page by Sei Motouchi. GH186 is a family of anomer-inverting enzymes from bacteria, members of which are specific for beta-1,2-glucans. Intriguingly, although some GH186 members work as classic glycoside hydrolases, others perform transglycosylation by wrapping the sugar chain around in the active-site, to position the 6-OH group of a terminal glucosyl unit for direct attack. Also notable, GH186 members appear to use an extended chain of water molecules to relay acceptor deprotonation by the general base residue, i.e. a Grotthuss mechanism. Check out the GH186 page to learn more about these interesting enzymes, and make sure to see the GH189, GH144, and GH162 pages from this same group.

2 May 2024: CBDs I to X... A major milestone! CBM families 1 to 10 are now complete! These are the old CBD (cellulose-binding domain) families, which used to have roman numerals as part of their nomenclature. A special thank you to all the authors and responsible curators who have contributed to this major milestone. Go have a peek at each of these old-school families on their respective CAZypedia pages: CBM1, CBM2, CBM3, CBM4, CBM5, CBM6, CBM7, CBM8, CBM9, and CBM10.

Retrieved from "http://www.cazypedia.org/index.php?title=Template:News&oldid=18651"