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Difference between revisions of "Polysaccharide Lyase Family 34"
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== Substrate specificities == | == Substrate specificities == | ||
| − | + | PL34 is a small family (28 sequences), mainly bacterial, with only one sequence belonging to the metazoan ''Knipowitschia caucasica'' ([http://www.cazy.org/PL34.html PL34])<cite>Drula2022</cite>. The founding member of family 34, and the only one characterized, belongs to OPIT5_18480 of Opitutaceae bacterium TAV5 (AHF91913.1). This enzyme presents an activity against alginate (EC 4.2.2.-) <cite>Helbert2019</cite>. | |
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== Kinetics and Mechanism == | == Kinetics and Mechanism == | ||
| − | + | Not determined | |
== Catalytic Residues == | == Catalytic Residues == | ||
| − | + | Not determined | |
== Three-dimensional structures == | == Three-dimensional structures == | ||
| − | + | Unsolved | |
== Family Firsts == | == Family Firsts == | ||
| − | ;First | + | ;First description of catalytic activity: Alginate lyase was the first activity discovered for the family PL34 <cite>Helbert2019</cite>. |
| − | ;First | + | ;First First charge neutralizer identification: To be determined |
| − | ;First | + | ;First Brønstead acid and base residue identification: To be determined |
| − | ;First 3-D structure: | + | ;First 3-D structure: To be determined |
== References == | == References == | ||
<biblio> | <biblio> | ||
| − | # | + | #Drula2022 pmid=34850161 |
| − | # | + | #Helbert2019 pmid=30850540 |
</biblio> | </biblio> | ||
[[Category:Polysaccharide Lyase Families|PL034]] | [[Category:Polysaccharide Lyase Families|PL034]] | ||
Revision as of 07:25, 23 August 2024
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
| Polysaccharide Lyase Family PL33 | |
| 3D Structure | |
| Mechanism | |
| Charge neutraliser | |
| Active site residues | |
| CAZy DB link | |
| https://www.cazy.org/PL33.html | |
Substrate specificities
PL34 is a small family (28 sequences), mainly bacterial, with only one sequence belonging to the metazoan Knipowitschia caucasica (PL34)[1]. The founding member of family 34, and the only one characterized, belongs to OPIT5_18480 of Opitutaceae bacterium TAV5 (AHF91913.1). This enzyme presents an activity against alginate (EC 4.2.2.-) [2].
Kinetics and Mechanism
Not determined
Catalytic Residues
Not determined
Three-dimensional structures
Unsolved
Family Firsts
- First description of catalytic activity
- Alginate lyase was the first activity discovered for the family PL34 [2].
- First First charge neutralizer identification
- To be determined
- First Brønstead acid and base residue identification
- To be determined
- First 3-D structure
- To be determined
References
- Drula E, Garron ML, Dogan S, Lombard V, Henrissat B, and Terrapon N. (2022). The carbohydrate-active enzyme database: functions and literature. Nucleic Acids Res. 2022;50(D1):D571-D577. DOI:10.1093/nar/gkab1045 |
- Helbert W, Poulet L, Drouillard S, Mathieu S, Loiodice M, Couturier M, Lombard V, Terrapon N, Turchetto J, Vincentelli R, and Henrissat B. (2019). Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space. Proc Natl Acad Sci U S A. 2019;116(13):6063-6068. DOI:10.1073/pnas.1815791116 |