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Difference between revisions of "Glycosyltransferase Family 138"
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== Substrate specificities == | == Substrate specificities == | ||
| − | GT138 family of glycosyltransferase is exemplified by AvrB that contains a Fido domain <cite>Peng2024</ | + | GT138 family of glycosyltransferase is exemplified by AvrB that contains a Fido domain <cite>Peng2024</citecite>Kinch2009</cite>. AvrB is a bacterial effector from the plant pathogen ''Pseudomonas syringae''. AvrB utilizes UDP-rhamnose or dTDP-rhamnose as a co-substrate to modify the host protein RIN4 and causes the programmed cell death (namely hypersensitive response). |
Authors may get an idea of what to put in each field from ''Curator Approved'' [[Glycosyltransferase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser window...)'' | Authors may get an idea of what to put in each field from ''Curator Approved'' [[Glycosyltransferase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser window...)'' | ||
Revision as of 23:03, 31 January 2025
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
| Glycosyltransferase Family GT138 | |
| Clan | Fido |
| Mechanism | Inverting |
| Active site residues | Known |
| CAZy DB link | |
| https://www.cazy.org/GT138.html | |
Substrate specificities
GT138 family of glycosyltransferase is exemplified by AvrB that contains a Fido domain [1, 2, 3]. AvrB is a bacterial effector from the plant pathogen Pseudomonas syringae. AvrB utilizes UDP-rhamnose or dTDP-rhamnose as a co-substrate to modify the host protein RIN4 and causes the programmed cell death (namely hypersensitive response).
Authors may get an idea of what to put in each field from Curator Approved Glycosyltransferase Families. (TIP: Right click with your mouse and open this link in a new browser window...)
In the meantime, please see these references for an essential introduction to the CAZy classification system: [4, 5].
Kinetics and Mechanism
Content is to be added here.
Catalytic Residues
Content is to be added here.
Three-dimensional structures
Content is to be added here.
Family Firsts
- First stereochemistry determination
- Content is to be added here.
- First catalytic nucleophile identification
- Content is to be added here.
- First general acid/base residue identification
- Content is to be added here.
- First 3-D structure
- Content is to be added here.
References
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Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. The Biochemist, vol. 30, no. 4., pp. 26-32. DOI:10.1042/BIO03004026.
- Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |