Lexicon

The entries listed below comprise a lexicon of key terms and concepts in CAZypedia. Specifically, the aim of the lexicon is to provide a precise definition of various specialized terms unique to carbohydrate chemistry [1, 2], as well as a general overview of the catalytic mechanisms of the major CAZyme classes [3, 4, 5, 6, 7].

Jump to: Curator Approved Lexicon pages | Lexicon pages under construction

Curator Approved

These pages have been approved by the Responsible Curator as essentially complete. CAZypedia is a living document, so further improvement of these pages is still possible; please see the individual pages for more information.

30 Lexicon entries have been Curator Approved.^(definition)

A

• Absolute configuration (D/L nomenclature)
• Alpha-glucan lyases
• Anomeric centre (alpha and beta)

C

• Carbohydrate Bioengineering Meetings
• Carbohydrate-active enzymes
• Carbohydrate-binding modules
• Catalytic nucleophile
• Cellulosome
• Clans
• Cohesin-dockerin interactions
• Conformational itinerary
• Conformational nomenclature

F

• Families

G

• General acid/base
• Glycoside hydrolases
• Glycosyltransferases

I

• Inverting glycoside hydrolase mechanism

N

• Neighboring group participation

O

• Oxazolinium ion
• Oxocarbenium ion

P

• Phosphorylases
• Polysaccharide epimerases

R

• Reaction intermediate
• Retaining glycoside hydrolase mechanism

S

• Sequence-based classification
• Sub-site nomenclature
• Surface Binding Site
• Syn/anti lateral protonation

T

• Transglycosylases
• Transition state

Under construction

These pages are currently under construction in CAZypedia. As such, the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information on these pages should therefore be considered to be under revision and may be subject to major changes.

1 Lexicon entries are currently under construction.^(definition)

P

• Polysaccharide Lyases

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References

3. Sinnott, M.L. (1990) Catalytic mechanisms of enzymic glycosyl transfer. Chem. Rev. 90, 1171-1202. DOI: 10.1021/cr00105a006

4. McCarter JD and Withers SG. (1994). Mechanisms of enzymatic glycoside hydrolysis. Curr Opin Struct Biol. 1994;4(6):885-92. DOI:10.1016/0959-440x(94)90271-2 |
5. Yip VL and Withers SG. (2006). Breakdown of oligosaccharides by the process of elimination. Curr Opin Chem Biol. 2006;10(2):147-55. DOI:10.1016/j.cbpa.2006.02.005 |
6. Vocadlo DJ and Davies GJ. (2008). Mechanistic insights into glycosidase chemistry. Curr Opin Chem Biol. 2008;12(5):539-55. DOI:10.1016/j.cbpa.2008.05.010 |
7. Lairson LL, Henrissat B, Davies GJ, and Withers SG. (2008). Glycosyltransferases: structures, functions, and mechanisms. Annu Rev Biochem. 2008;77:521-55. DOI:10.1146/annurev.biochem.76.061005.092322 |