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Lexicon
The pages listed below comprise a lexicon of key terms and concepts in CAZypedia. Specifically, the aim of the lexicon is to provide a precise definition of various specialized terms unique to carbohydrate chemistry [1, 2], as well as a general overview of the catalytic mechanisms of the major CAZyme classes [3, 4, 5, 6].
Curator Approved
There are currently 24 Curator Approved(definition) Lexicon pages in CAZypedia.
- Absolute configuration (D/L nomenclature)
- Alpha-glucan lyases
- Anomeric centre (alpha and beta)
- Carbohydrate Bioengineering Meetings
- Carbohydrate-active enzymes
- Carbohydrate-binding modules
- Catalytic nucleophile
- Cellulosome
- Conformational itinerary
- Conformational nomenclature
- General acid/base
- Glycoside hydrolases
- Glycosyltransferases
- Oxazolinium ion
- Oxocarbenium ion
- Phosphorylases
- Polysaccharide epimerases
- Reaction intermediate
- Sequence-based classification
- Sub-site nomenclature
- Surface Binding Site
- Syn/anti lateral protonation
- Transglycosylases
- Transition state
Under construction
There are currently 1 Lexicon pages under construction(definition) in CAZypedia.
References
- McCarter JD and Withers SG. (1994). Mechanisms of enzymatic glycoside hydrolysis. Curr Opin Struct Biol. 1994;4(6):885-92. DOI:10.1016/0959-440x(94)90271-2 |
- Vocadlo DJ and Davies GJ. (2008). Mechanistic insights into glycosidase chemistry. Curr Opin Chem Biol. 2008;12(5):539-55. DOI:10.1016/j.cbpa.2008.05.010 |
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Sinnott, M.L. (1990) Catalytic mechanisms of enzymic glycosyl transfer. Chem. Rev. 90, 1171-1202. DOI: 10.1021/cr00105a006
- Lairson LL, Henrissat B, Davies GJ, and Withers SG. (2008). Glycosyltransferases: structures, functions, and mechanisms. Annu Rev Biochem. 2008;77:521-55. DOI:10.1146/annurev.biochem.76.061005.092322 |