CAZypedia celebrates the life of Senior Curator Emeritus Harry Gilbert, a true giant in the field, who passed away in September 2025.

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Difference between revisions of "Template:News"

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'''20 June 2011:''' ''More phosphorylases:'' On May 29, [[Author]] and [[Responsible Curator]] '''[[User:Hiroyuki Nakai|Hiroyuki Nakai]]''' completed the '''[[Glycoside Hydrolase Family 65]]''' page.  '''[[GH65]]''' is comprised of alpha-glycoside phosphorylases and alpha,alpha-trehalose hydrolases. Due to the readily reversible nature of phosphorolysis, '''[[GH65]]''' enzymes have been harnessed for glycoside synthesis, including recent work by '''[[User:Hiroyuki Nakai|Dr. Nakai]]'''. The completion of the '''[[GH65]]''' complements previously completed pages on the beta-glycoside phosphorylases of [[GH94]] and [[GH112]] in ''CAZypedia''.
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'''31 October 2025:''' ''A spooktacular addition to the CAZypedia family!'' Come and say 'Boo!' to the frighteningly well written '''[[CBM13]]''' ''CAZypedia'' page.  The '''[[CBM13]]''' family is a '''[[Carbohydrate-binding_modules#Blurred Lines: CBMs, Lectins and Outliers|lectin-like CBM family]]'''. Its first characterized members were lectins, including the B chain from the highly toxic [https://en.wikipedia.org/wiki/Ricin ricin] toxin from ''Ricinus communis''.  This spine tingling read was authored by '''[[User:Scott Mazurkewich|Scott Mazurkewich]]''' and '''[[User:Lauren McKee|Lauren McKee]]''' who also acted as responsible curator. ''Come and visit the scariest of ''CAZypedia'' CBM pages, '''[[CBM13|here!]]'''...  if you dare...''
 
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'''12 May 2011:''' ''A new page on a new-ish family:'' [[Author]] and [[Responsible Curator]] '''[[User:Satoshi Kaneko|Satoshi Kaneko]]'''  completed the '''[[Glycoside Hydrolase Family 115]]''' page today. '''[[GH115]]''' contains microbial alpha-glucuronidases, which are involved the cleavage of D-glucuronic acid and 4-O-methyl-D-glucuronic acid sidechains from xylans.  Remarkably, '''[[GH115]]''' enzymes can release these monosaccharides from intact polymer chains, which is rather rare for exo-acting enzymes, and contrasts them with glucuronidases from '''[[GH67]]'''.  Although this regiospecific activity has been known since the last millenium, it was only in 2009 that these particular enzymes nucleated their own GH family.
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'''29 July 2025:''' ''[[CBM91]] is in the news!''  The xylan binding '''[[CBM91]]''' family ''CAZypedia'' page is up and running.  Appended to mainly [[GH43]] xylanases this [[CBM91]] family drives interaction with substrate. The [[CBM91]] page was authored by '''[[User:Daichi Ito|Daichi Ito]]''' who also discovered the initial xylan-binding function which resulted in the creation of the [[CBM91]] CAZy family. ''Read up on this industrially interesting '''[[CBM91]]''' family '''[[CBM91|here]]'''.''
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'''09 May 2011:''' ''It's a big news day here at CAZypedia.'' We are proud to announce that three distinct glycoside hydrolase family pages have been [[Curator Approved]] today:
 
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* '''[[Glycoside Hydrolase Family 74]]''' (written by '''[[User:Katsuro Yaoi|Katsuro Yaoi]]''' and '''[[User:Takuya Ishida|Takuya Ishida]]''', and curated by '''[[User:Katsuro Yaoi|Katsuro Yaoi]]''') is a family predominantly comprised of endo-glucanases that are specific for the plant polysaccharide xyloglucan (true xyloglucanases).
 
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* '''[[Glycoside Hydrolase Family 95]]''' (written and curated by '''[[User:Takane Katayama|Takane Katayama]]''') is a family of 1,2-α-L-fucosidases, members of which cleave human milk oligosaccharides, blood group glycoconjugates, and/or xyloglucan oligosaccharides.
 
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* '''[[Glycoside Hydrolase Family 117]]''' (written by '''[[User:Etienne Rebuffet|Etienne Rebuffet]]''' and curated by '''[[User:Mirjam Czjzek|Mirjam Czjzek]]''') is a small, newly created family of α-1,3-L-(3,6-anhydro)-galactosidases (neoagarobiose hydrolases), which catalyze the final step in the degradation of agars from red macroalgae in the marine environment.
 
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''We would like to express our sincere thanks to our Japanese and French colleagues for these important contributions to CAZypedia.''  Links to these families will be included in the next public update of the [http://www.cazy.org/ CAZy database] (expected soon!).
 
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''Special thanks also go to'' '''[[User:Etienne Rebuffet|Etienne]]''' ''for updating the'' '''[[Glycoside Hydrolase Family 82]]''' ''page,'' including a very cool animated image that highlights enzyme domain movement during substrate binding - CAZypedia really is a living resource that can be continually improved with the latest knowledge.
 
 
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Latest revision as of 10:50, 3 November 2025

31 October 2025: A spooktacular addition to the CAZypedia family! Come and say 'Boo!' to the frighteningly well written CBM13 CAZypedia page. The CBM13 family is a lectin-like CBM family. Its first characterized members were lectins, including the B chain from the highly toxic ricin toxin from Ricinus communis. This spine tingling read was authored by Scott Mazurkewich and Lauren McKee who also acted as responsible curator. Come and visit the scariest of CAZypedia CBM pages, here!... if you dare...

29 July 2025: CBM91 is in the news! The xylan binding CBM91 family CAZypedia page is up and running. Appended to mainly GH43 xylanases this CBM91 family drives interaction with substrate. The CBM91 page was authored by Daichi Ito who also discovered the initial xylan-binding function which resulted in the creation of the CBM91 CAZy family. Read up on this industrially interesting CBM91 family here.

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