CAZypedia celebrates the life of Senior Curator Emeritus Harry Gilbert, a true giant in the field, who passed away in September 2025.


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Difference between revisions of "Template:News"

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'''18 July 2011:''' ''Our second GH-I chitosanase page:'' '''[[User:Ryszard Brzezinski|Ryszard Brzezinski]]''' has recently completed and [[:Category:Curator approved|Curator Approved]] his second page on chitosanases, enzymes which act specifically on the de-acetylated form of chitin (the polysaccharide chitin is a widespread in Nature as a main component of insect bodies and crustacean shells).  '''[[Glycoside Hydrolase Family 80]]''', a member of [[Clan]] GH-I together with [[GH24]] and [[GH46]], is a remarkably small family, which has thus far received only limited experimental attention.  We therefore look forward to the expansion of this page with structural and mechanistic data in the future. ''Coincidentally, the '''[[GH80]]''' page is our '''80th''' [[:Category:Curator approved|Curator Approved]] [[Glycoside Hydrolase Families|Glycoside Hydrolase Family]] page in CAZypedia!''
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'''31 October 2025:''' ''A spooktacular addition to the CAZypedia family!'' Come and say 'Boo!' to the frighteningly well written '''[[CBM13]]''' ''CAZypedia'' page.  The '''[[CBM13]]''' family is a '''[[Carbohydrate-binding_modules#Blurred Lines: CBMs, Lectins and Outliers|lectin-like CBM family]]'''. Its first characterized members were lectins, including the B chain from the highly toxic [https://en.wikipedia.org/wiki/Ricin ricin] toxin from ''Ricinus communis''.  This spine tingling read was authored by '''[[User:Scott Mazurkewich|Scott Mazurkewich]]''' and '''[[User:Lauren McKee|Lauren McKee]]''' who also acted as responsible curator. ''Come and visit the scariest of ''CAZypedia'' CBM pages, '''[[CBM13|here!]]'''...  if you dare...'' 
 
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'''20 June 2011:''' ''More phosphorylases:'' On May 29, [[Author]] and [[Responsible Curator]] '''[[User:Hiroyuki Nakai|Hiroyuki Nakai]]'''  completed the '''[[Glycoside Hydrolase Family 65]]''' page.  '''[[GH65]]''' is comprised of alpha-glycoside phosphorylases and alpha,alpha-trehalose hydrolases. Due to the readily reversible nature of phosphorolysis, '''[[GH65]]''' enzymes have been harnessed for glycoside synthesis, including recent work by '''[[User:Hiroyuki Nakai|Dr. Nakai]]'''. The completion of the '''[[GH65]]''' complements previously completed pages on the beta-glycoside phosphorylases of [[GH94]] and [[GH112]] in ''CAZypedia''.
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'''29 July 2025:''' ''[[CBM91]] is in the news!''  The xylan binding '''[[CBM91]]''' family ''CAZypedia'' page is up and running. Appended to mainly [[GH43]] xylanases this [[CBM91]] family drives interaction with substrate. The [[CBM91]] page was authored by '''[[User:Daichi Ito|Daichi Ito]]''' who also discovered the initial xylan-binding function which resulted in the creation of the [[CBM91]] CAZy family. ''Read up on this industrially interesting '''[[CBM91]]''' family '''[[CBM91|here]]'''.''
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'''12 May 2011:''' ''A new page on a new-ish family:'' [[Author]] and [[Responsible Curator]] '''[[User:Satoshi Kaneko|Satoshi Kaneko]]''' completed the '''[[Glycoside Hydrolase Family 115]]''' page today.  '''[[GH115]]''' contains microbial alpha-glucuronidases, which are involved the cleavage of D-glucuronic acid and 4-O-methyl-D-glucuronic acid sidechains from xylans.  Remarkably, '''[[GH115]]''' enzymes can release these monosaccharides from intact polymer chains, which is rather rare for exo-acting enzymes, and contrasts them with glucuronidases from '''[[GH67]]'''.  Although this regiospecific activity has been known since the last millenium, it was only in 2009 that these particular enzymes nucleated their own GH family.
 
 
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Latest revision as of 10:50, 3 November 2025

31 October 2025: A spooktacular addition to the CAZypedia family! Come and say 'Boo!' to the frighteningly well written CBM13 CAZypedia page. The CBM13 family is a lectin-like CBM family. Its first characterized members were lectins, including the B chain from the highly toxic ricin toxin from Ricinus communis. This spine tingling read was authored by Scott Mazurkewich and Lauren McKee who also acted as responsible curator. Come and visit the scariest of CAZypedia CBM pages, here!... if you dare...


29 July 2025: CBM91 is in the news! The xylan binding CBM91 family CAZypedia page is up and running. Appended to mainly GH43 xylanases this CBM91 family drives interaction with substrate. The CBM91 page was authored by Daichi Ito who also discovered the initial xylan-binding function which resulted in the creation of the CBM91 CAZy family. Read up on this industrially interesting CBM91 family here.